Description

2-Bromo-3-Fluoro-3-Methylbutyric Acid is a versatile halogenated carboxylic acid building block of significant interest in advanced organic synthesis. Its value lies in the strategic placement of bromine and fluorine atoms on a branched carbon skeleton, enabling precise molecular construction. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of fluorinated drug candidates, particularly in protease inhibitor and kinase inhibitor research.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Fluorine Chemistry Research: Serves as a valuable substrate for studying nucleophilic substitution and elimination reactions involving halogenated centers.
• Ligand and Catalyst Development: The carboxylic acid functionality allows for conversion into amides or esters for use in chiral auxiliaries or metal-chelating ligands.
• Material Science Precursor: Potential building block for specialty polymers and liquid crystals that incorporate halogenated motifs for modified physical properties.

Basic Information

Product Name	2-Bromo-3-Fluoro-3-Methylbutyric Acid
CAS No.	50884-94-1
Molecular Formula	C5H8BrFO2
Molecular Weight	199.02 g/mol
Synonyms	3-Methyl-2-bromo-3-fluorobutyric Acid; 2-Bromo-3-fluoro-3-methylbutanoic Acid; α-Bromo-β-fluoro-β-methylbutyric Acid; Butyric acid, 2-bromo-3-fluoro-3-methyl-; 50884-94-1
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Fluoro-3-Methylbutyric Acid is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including chromatographic purity assessment and structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its acidic nature, keep away from strong bases and incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.