Description

Acth (4-7) is a synthetic peptide fragment of the adrenocorticotropic hormone (ACTH), specifically encompassing amino acids 4 through 7. This compound is of significant interest in biochemical research and pharmaceutical development due to its role in studying melanocortin receptor interactions and neuroprotective mechanisms. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies focused on neuroscience, dermatology, and peptide-based therapeutic discovery.

Application

• Neuroscientific Research: Used as a tool compound to study the effects of ACTH fragments on learning, memory, and attention processes.
• Dermatological Studies: Investigated for its potential role in melanogenesis (skin pigmentation) and related signaling pathways.
• Pharmaceutical R&D: Serves as a key intermediate or reference standard in the development of novel peptide therapeutics targeting melanocortin receptors (MC1R, MC4R).
• Biochemical Assays: Employed in receptor binding studies and in vitro bioactivity tests to characterize peptide-receptor interactions.
• Academic Research: Utilized in university and institutional labs for fundamental research into the structure-activity relationships (SAR) of neuropeptides.

Basic Information

Product Name	Acth (4-7)
CAS No.	50842-42-7
Molecular Formula	C22H34N8O7
Molecular Weight	522.56 g/mol
Synonyms	ACTH (4-7); Adrenocorticotropic Hormone (4-7); H-Met-Glu-His-Phe-OH; Melanotropin (4-7); ACTH Fragment 4-7; Tetrapeptide ACTH(4-7); Met-Glu-His-Phe; L-Methionyl-L-α-glutamyl-L-histidyl-L-phenylalanine
EINECS	Contact for details

Quality Control

Our Acth (4-7) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 8.0%
Peptide Content	≥ 70.0%
Amino Acid Analysis	± 10% of theoretical

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.