Description

Glycine, n-[(2-Methoxy-1,1-Dimethylethoxy)Carbonyl]- (9Ci) is a specialized, protected amino acid derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its role in facilitating complex peptide coupling reactions while preventing unwanted side reactions at the glycine residue. Pharmaceutical researchers and fine chemical manufacturers need it for the development of novel therapeutic peptides, peptidomimetics, and other bioactive molecules where precise molecular architecture is paramount.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key intermediate for the controlled incorporation of glycine into peptide chains, particularly in Fmoc/t-Bu strategies.
• Pharmaceutical Intermediates: Used in the research and development of peptide-based drugs, including hormone analogs and enzyme inhibitors.
• Bioconjugation: Employed in the synthesis of peptide tags, linkers, and probes for labeling proteins and other biomolecules.
• Combinatorial Chemistry: A valuable building block for creating diverse chemical libraries in drug discovery platforms.
• Agrochemical Research: Potential use in the synthesis of novel, bioactive peptide-inspired crop protection agents.
• Academic & Industrial R&D: Serves as a reagent for methodological studies in organic chemistry and new synthetic route development.

Basic Information

Item	Details
Product Name	Glycine, n-[(2-Methoxy-1,1-Dimethylethoxy)Carbonyl]- (9Ci)
CAS No.	50841-86-6
Molecular Formula	C9H17NO5
Molecular Weight	219.24 g/mol
Synonyms	N-[(2-Methoxy-1,1-dimethylethoxy)carbonyl]glycine; N-(2-Methoxy-1,1-dimethylethoxycarbonyl)glycine; Glycine, N-[(2-methoxy-1,1-dimethylethoxy)carbonyl]-; N-(MOC-Gly) (abbrev.); N-(1-Methoxy-2-methylpropan-2-yloxycarbonyl)glycine; Glycine, N-[(1-methoxy-2-methyl-2-propoxy)carbonyl]-; Boc-Gly-OMe derivative (related); Protected Glycine Derivative
EINECS	Contact for details

Quality Control

Our Glycine, n-[(2-Methoxy-1,1-Dimethylethoxy)Carbonyl]- (9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with full characterization data are provided to support your R&D and cGMP manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.