Description

3-[Bis(1,1-Dimethylethyl)Phosphino]Propenoic Acid Methyl Ester is a specialized organophosphorus compound that serves as a valuable ligand precursor in advanced catalytic systems. Its primary commercial value lies in its ability to facilitate highly selective and efficient transition metal-catalyzed reactions, which are critical for synthesizing complex molecules. This product is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries, where it enables the production of high-value intermediates and active ingredients.

Application

• Pharmaceutical Intermediate Synthesis: As a key ligand precursor in cross-coupling reactions (e.g., Suzuki, Heck) for constructing complex drug molecules.
• Agrochemical Manufacturing: Used in catalytic processes to create novel, high-performance active ingredients for crop protection.
• Fine Chemical Production: Enables selective hydrogenation and other metal-catalyzed transformations in the synthesis of specialty chemicals.
• Catalyst Development: Serves as a building block for creating bespoke phosphine ligands in homogeneous catalysis research.
• Material Science Research: Potential application in the synthesis of novel organometallic complexes and polymers.
• Academic & Industrial R&D: A critical reagent for methodology development in organic and organometallic chemistry.

Basic Information

Item	Detail
Product Name	3-[Bis(1,1-Dimethylethyl)Phosphino]Propenoic Acid Methyl Ester
CAS No.	50838-19-2
Molecular Formula	C13H25O2P
Molecular Weight	244.31 g/mol
Synonyms	Methyl 3-(Di-tert-butylphosphino)acrylate; Di-tert-butylphosphinoacrylic Acid Methyl Ester; 3-(Di-tert-butylphosphino)acrylic Acid Methyl Ester; Methyl 3-(Bis(1,1-dimethylethyl)phosphino)-2-propenoate; (Di-tert-butylphosphino)acrylic Acid Methyl Ester; Ligand Precursor 50838-19-2; t-Bu2P-acrylate Methyl Ester
EINECS	Contact for details

Quality Control

Our production of 3-[Bis(1,1-Dimethylethyl)Phosphino]Propenoic Acid Methyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive catalytic applications. All materials undergo comprehensive analytical characterization, including NMR, HPLC, and GC analysis, to verify identity, purity, and the absence of critical metallic impurities. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Due to its sensitivity to oxidation, this material should be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.