Description

Hemoglobin St. Louis is a well-characterized variant of hemoglobin, a critical oxygen-transporting metalloprotein found in red blood cells. This specific mutant form is of significant interest in biochemical and clinical research for studying the structure-function relationships of hemoglobin and the pathophysiology of related blood disorders. It serves as an essential reference standard and research reagent for scientists in biomedical research, clinical diagnostics, and pharmaceutical development, particularly those investigating hemoglobinopathies and oxygen transport mechanisms.

Application

• Biochemical Research: Used as a high-purity reference standard in studies of hemoglobin structure, oxygen-binding kinetics, and allosteric regulation.
• Clinical Diagnostics: Serves as a control material in the development and validation of diagnostic assays for detecting abnormal hemoglobin variants.
• Pharmaceutical R&D: Employed in drug discovery programs targeting sickle cell disease, thalassemia, and other hemoglobin-related disorders.
• Academic Studies: A key reagent for university and institutional research into molecular hematology and protein biochemistry.
• Biotechnology: Potential use in the development of hemoglobin-based oxygen carriers (HBOCs) and other therapeutic platforms.

Basic Information

Product Name	Hemoglobin St. Louis
CAS No.	50814-89-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Hb St. Louis; Hemoglobin Saint Louis; Unstable Hemoglobin St. Louis; Hemoglobin beta 28 (B10) Leu replaced by Gln; Hemoglobin variant St. Louis; HBB: c.86T>A (p.Leu29Gln); Hemoglobin Mutant St. Louis
EINECS	Contact for details

Quality Control

Our Hemoglobin St. Louis is produced and handled under stringent quality protocols to ensure batch-to-batch consistency and purity suitable for research applications. Each lot is characterized using advanced analytical techniques. Certificates of Analysis (COA) detailing purity, identity, and other relevant parameters are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	Lyophilized powder
Identification (IR / HPLC)	Conforms to standard
Purity (HPLC)	≥ 95%
Protein Content (Biuret)	≥ 90%
Methemoglobin Content	< 5%
Solubility	Clear solution in buffer
Water Content (KF)	< 5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.