Description

Hemoglobin F Malta I CAS NO 50814-87-4 is a specific fetal hemoglobin variant, a globular protein of significant biochemical and clinical interest. This compound is a critical reference standard and research material for studying hemoglobinopathies and developmental biology. It is primarily utilized by diagnostic manufacturers, clinical research organizations, and academic institutions focused on hematology and genetic disorders.

Application

• Clinical Diagnostic Reference Standard: Used as a calibrator or control in assays for detecting and quantifying fetal hemoglobin (HbF) variants.
• Biomedical Research: Essential for in-vitro studies on hemoglobin switching, gene expression, and the molecular pathology of thalassemias.
• Pharmaceutical Development: Serves as a model compound in drug discovery programs targeting sickle cell disease and β-thalassemia.
• Quality Control Reagent: Employed by in-vitro diagnostic (IVD) kit manufacturers to validate the performance of hemoglobin electrophoresis or HPLC systems.
• Biochemical Studies: Used to investigate oxygen-binding kinetics, protein stability, and the functional impact of specific amino acid substitutions.
• Educational Material: Supplied to university laboratories for advanced teaching in molecular hematology and protein chemistry.

Basic Information

Product Name	Hemoglobin F Malta I
CAS No.	50814-87-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Hb F Malta I; Hemoglobin F Malta-I; Fetal Hemoglobin Malta I; γ-Globin variant Malta I; HbF Malta I; Hemoglobin F Malte I; Hemoglobin F Malta 1
EINECS	Contact for details

Quality Control

Our Hemoglobin F Malta I is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical characterization, including purity assessment by HPLC and identity confirmation via mass spectrometry. A Certificate of Analysis (COA) detailing batch-specific results is provided to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	Lyophilized powder
Identification (HPLC/MS)	Conforms to standard
Purity (HPLC)	≥ 95%
Solubility	Soluble in appropriate aqueous buffers
Protein Content	Determined by UV absorbance
Endotoxin Level	< 1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.