Description

Carbobenzoxy-Dl-Glutamine is a protected derivative of the amino acid glutamine, widely used as a key synthetic intermediate in peptide chemistry. Its primary value lies in providing a versatile building block for the controlled synthesis of complex peptides and peptidomimetics, where it protects the reactive amine group during coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors, particularly those involved in developing novel therapeutic peptides and biochemical probes.

Application

• Peptide Synthesis: A fundamental building block (Cbz-protected amino acid) for solid-phase and solution-phase peptide synthesis.
• Pharmaceutical Intermediates: Serves as a critical precursor in the research and development of peptide-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used in the study of enzyme substrates, inhibitors, and the structure-activity relationships (SAR) of glutamine-containing peptides.
• Proteomics & Molecular Biology: Employed in the synthesis of custom peptides for antibody production, protein labeling, and cell signaling studies.
• Combinatorial Chemistry: A valuable reagent in libraries for drug discovery and high-throughput screening applications.

Basic Information

Product Name	Carbobenzoxy-Dl-Glutamine
CAS No.	50516-14-8
Molecular Formula	C₁₃H₁₆N₂O₅
Molecular Weight	280.28 g/mol
Synonyms	N-Carbobenzoxy-DL-glutamine; Cbz-DL-Gln-OH; Z-DL-Gln-OH; N-(Benzyloxycarbonyl)-DL-glutamine; Benzyl N-(DL-4-amino-4-carboxybutyl)carbamate; DL-2-(Benzyloxycarbonylamino)-4-carbamoylbutanoic acid; Nα-Carbobenzoxy-DL-glutamine; CBZ-DL-Glutamine
EINECS	Contact for details

Quality Control

Our Carbobenzoxy-Dl-Glutamine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Purity (Chiral HPLC)	DL-mixture (Racemic)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.