Description

4-Amino-3-Bromobenzonitrile is a versatile aromatic nitrile and halogenated aniline derivative, serving as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both an amino and a bromo substituent on the benzonitrile core, makes it a highly valuable intermediate for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, where it is used to develop active ingredients, functional dyes, and specialty polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and plant growth regulators.
• Material Science: Monomer or precursor for high-performance polymers, liquid crystals, and organic electronic materials.
• Dye & Pigment Manufacturing: Intermediate in the production of advanced colorants and functional dyes.
• Cross-Coupling Reactions: Serves as a substrate in Buchwald-Hartwig amination and Suzuki-Miyaura cross-coupling reactions to form complex biaryl structures.
• Research & Development: Valuable reagent in academic and industrial R&D for exploring new chemical entities and synthetic pathways.

Basic Information

Product Name	4-Amino-3-Bromobenzonitrile
CAS No.	50397-74-5
Molecular Formula	C7H5BrN2
Molecular Weight	197.04 g/mol
Synonyms	3-Bromo-4-aminobenzonitrile; 4-Amino-3-bromobenzonitrile; 3-Bromo-4-cyanobenzenamine; Benzonitrile, 4-amino-3-bromo-; 4-Cyano-2-bromoaniline; 2-Bromo-4-cyanobenzenamine; 3-Bromo-4-aminophenyl cyanide
EINECS	Contact for details

Quality Control

Our 4-Amino-3-Bromobenzonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to verify identity, potency, and impurity profiles. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	145 - 150 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.