Description

2-(Thiazol-5-Yl)Acetonitrile is a versatile heterocyclic nitrile building block, essential for constructing complex molecular architectures in advanced organic synthesis. Its core value lies in its bifunctional reactivity, where the nitrile group and the electron-deficient thiazole ring serve as key handles for further chemical transformations. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting infectious diseases or central nervous system disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole moiety.
• Ligand and Catalyst Precursor: Serves as a starting material for the preparation of specialized ligands used in transition metal catalysis.
• Material Science: Employed in the synthesis of functional polymers and organic electronic materials due to its conjugated system.
• Chemical Biology Probe Development: Utilized to create molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A critical raw material for fine chemical companies offering bespoke synthesis services.

Basic Information

Product Name	2-(Thiazol-5-Yl)Acetonitrile
CAS No.	50382-34-8
Molecular Formula	C5H4N2S
Molecular Weight	124.16 g/mol
Synonyms	5-Thiazoleacetonitrile; (Thiazol-5-yl)acetonitrile; 2-Thiazol-5-ylacetonitrile; 5-Cyanomethylthiazole; 2-(1,3-Thiazol-5-yl)acetonitrile; 5-(Cyanomethyl)thiazole; Thiazole-5-acetonitrile
EINECS	Contact for details

Quality Control

Our 2-(Thiazol-5-Yl)Acetonitrile is produced under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to traceability and documentation supports our customers' regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can compromise product quality. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.