Description

(6R)-7β-[[[(2,5-Dichlorophenyl)Thio]Acetyl]Amino]-3-[[(1-Methyl-1H-Tetrazol-5-Yl)Thio]Methyl]Cepham-3-Ene-4-Carboxylic Acid CAS NO 50368-34-8 is a high-purity, advanced pharmaceutical intermediate belonging to the cephem class of β-lactam antibiotics. This compound is a critical building block in the synthesis of potent third-generation cephalosporin antibiotics, valued for its role in creating broad-spectrum antimicrobial agents. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in the development and production of novel antibacterial drugs.

Application

This high-value intermediate is designed for specialized applications in the life sciences sector, particularly in antibiotic development.

• Active Pharmaceutical Ingredient (API) Synthesis: A key precursor in the multi-step synthesis of advanced cephalosporin antibiotics.
• Pharmaceutical Research & Development: Used in medicinal chemistry for the design and testing of new antibacterial compounds with improved efficacy and resistance profiles.
• Process Chemistry & Scale-Up: Employed in optimizing manufacturing routes for cephalosporin APIs, from laboratory scale to commercial production.
• Reference Standard: Serves as a certified reference material for quality control and analytical method development in pharmaceutical laboratories.

Basic Information

Item	Details
Product Name	(6R)-7β-[[[(2,5-Dichlorophenyl)Thio]Acetyl]Amino]-3-[[(1-Methyl-1H-Tetrazol-5-Yl)Thio]Methyl]Cepham-3-Ene-4-Carboxylic Acid
CAS No.	50368-34-8
Molecular Formula	C19H17Cl2N7O3S2
Molecular Weight	534.41 g/mol
Synonyms	7β-[(2,5-Dichlorophenylthio)acetamido]-3-[(1-methyl-1H-tetrazol-5-ylthio)methyl]-3-cephem-4-carboxylic Acid; Cefmenoxime Intermediate; Cefmenoxime Impurity; Cefmenoxime Related Compound A; (6R,7R)-7-[[(2,5-Dichlorophenylthio)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid; SC E 1365 Intermediate; Antibiotic Intermediate
EINECS	Contact for details

Quality Control

Our production of this pharmaceutical intermediate adheres to stringent quality systems. Every batch is subjected to comprehensive analytical testing, including HPLC for purity and related substances, IR and NMR for structural confirmation, and residual solvent analysis. We provide detailed Certificates of Analysis (COA) with each shipment, ensuring traceability and compliance with customer specifications and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.2%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.