Description

3-Pentynoyl-Coenzyme A is a specialized biochemical reagent and a key intermediate in the study of fatty acid metabolism and enzyme kinetics. This compound matters for researchers and manufacturers requiring high-purity, well-characterized coenzyme A derivatives for metabolic pathway analysis and inhibitor studies. It is primarily needed by the life sciences sector, including pharmaceutical R&D, academic biochemistry laboratories, and diagnostic kit manufacturers focusing on metabolic disorders.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic assays to study fatty acid oxidation and synthesis pathways.
• Pharmaceutical Development: Serves as a critical intermediate in the research and development of novel therapeutics targeting metabolic diseases.
• Diagnostic Reagent Manufacturing: Incorporated into in-vitro diagnostic kits for the detection and quantification of specific enzymatic activities related to metabolism.
• Enzyme Kinetics Studies: Employed to determine kinetic parameters (Km, Vmax) of acyl-CoA dehydrogenases and related enzymes.
• Metabolomics and Proteomics: Used as a standard or probe in mass spectrometry-based studies to identify and quantify metabolic intermediates.

Basic Information

Item	Detail
Product Name	3-Pentynoyl-Coenzyme A
CAS No.	50347-26-7
Molecular Formula	C₂₆H₄₂N₇O₁₇P₃S
Molecular Weight	849.63 g/mol
Synonyms	3-Pentynoyl-CoA; 3-Pentynoyl Coenzyme A; Pent-3-ynoyl-CoA; Coenzyme A, S-(3-pentynoate); 3-Pentynoic acid coenzyme A thioester; S-(3-Pentynoyl)coenzyme A; 3-Butyn-1-yl-CoA (common misnomer); Acetylene fatty acyl-CoA analog
EINECS	Contact for details

Quality Control

Our 3-Pentynoyl-Coenzyme A is produced under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for sensitive research applications. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment. For long-term stability, store as supplied and avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 3.0%
Biological Activity	Confirmed via enzymatic assay (upon request)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.