Description

(6R)-3-(Acetoxymethyl)-7-Methoxy-8-Oxo-7-(2-Thienylacetamido)-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid is a key advanced pharmaceutical intermediate, specifically a cephalosporin nucleus derivative. This compound is of critical importance for the synthesis of next-generation β-lactam antibiotics, offering a foundational structure for developing potent antimicrobial agents. It is primarily required by pharmaceutical R&D laboratories and manufacturers specializing in active pharmaceutical ingredient (API) production for anti-infective drugs.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of advanced cephalosporin antibiotics.
• Antibiotic R&D: Used in research and development for creating novel β-lactam compounds with improved efficacy and spectrum of activity.
• API Manufacturing: Employed in the production scale-up of active pharmaceutical ingredients for commercial antibiotic formulations.
• Chemical Synthesis Studies: Utilized in academic and industrial laboratories for studying structure-activity relationships (SAR) in medicinal chemistry.
• Process Chemistry: Acts as a standard or reference material for developing and optimizing synthetic pathways for complex pharmaceutical molecules.

Basic Information

Item	Detail
Product Name	(6R)-3-(Acetoxymethyl)-7-Methoxy-8-Oxo-7-(2-Thienylacetamido)-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid
CAS No.	50268-65-0
Molecular Formula	C18H18N2O7S2
Molecular Weight	438.48 g/mol
Synonyms	7-Methoxy-7-(2-thienylacetamido)-3-(acetoxymethyl)ceph-3-em-4-carboxylic acid; 7-Methoxy-7-(2-thienylacetamido)cephalosporanic acid; 7-Methoxy-7-(2-thienylacetamido)-3-acetoxymethyl-3-cephem-4-carboxylic acid; Cephalosporin C-3' nucleus derivative; 7-ADCA derivative; (6R,7R)-3-(Acetoxymethyl)-7-methoxy-8-oxo-7-(2-thienylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our (6R)-3-(Acetoxymethyl)-7-Methoxy-8-Oxo-7-(2-Thienylacetamido)-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a dry environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.