Description

H-Lys(Isopropyl)-Oh is a protected derivative of the essential amino acid L-lysine, featuring an isopropyl ester group. This modification is crucial for peptide synthesis, as it provides a versatile protecting group that can be selectively removed under mild conditions. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel peptides, bioactive compounds, and therapeutic agents.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key building block for the controlled incorporation of lysine residues into peptide chains.
• Solution-Phase Peptide Chemistry: Used in classical synthesis strategies for complex or sensitive peptide sequences.
• Pharmaceutical Intermediate: Serves as a critical precursor in the research and development of peptide-based drugs and APIs.
• Bioconjugation and Labeling: The reactive functional groups enable site-specific attachment of probes, tags, or payloads.
• Biochemical Research: Employed in studying protein-protein interactions, enzyme substrates, and receptor ligands.
• Material Science: Can be used to synthesize peptide-modified polymers or surfaces with specific biological functionalities.

Basic Information

Product Name	H-Lys(Isopropyl)-Oh
CAS No.	5977-09-3
Molecular Formula	C9H20N2O2
Molecular Weight	188.27 g/mol
Synonyms	Nα-Boc-Nε-Cbz-L-lysine isopropyl ester; Boc-Lys(Cbz)-O-iPr; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-((tert-butoxycarbonyl)amino)hexanoic acid; Fmoc-Lys(Boc)-OH; L-Lysine, N2-[(1,1-dimethylethoxy)carbonyl]-N6-[(phenylmethoxy)carbonyl]-, 1-methylethyl ester; Boc-Lys(Z)-O-iPr; Nα-Boc-Nε-Z-L-lysine isopropyl ester; Protected L-Lysine isopropyl ester
EINECS	Contact for details

Quality Control

Our H-Lys(Isopropyl)-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, chiral purity, and residual solvent levels is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed in a desiccated environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.