Description

Ethyl 4-(4-Fluorophenyl)-1 2 3 4-Tetrahydroisoquinoline-3-carboxylate is a high-purity fluorinated tetrahydroisoquinoline derivative, a critical building block in modern organic synthesis. This compound is valued for its precise molecular architecture, which enables the construction of complex molecules with targeted biological activity. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, cardiovascular diseases, and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the fluorophenyl and tetrahydroisoquinoline motifs can contribute to biological efficacy and environmental stability.
• Chemical Biology Probe Synthesis: Serves as a scaffold for creating molecular probes to study enzyme function and protein-ligand interactions in biological systems.
• Material Science Research: Investigated as a monomer or additive for creating specialized polymers with unique optical or electronic properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and the exploration of new synthetic pathways in heterocyclic chemistry.

Basic Information

Product Name	Ethyl 4-(4-Fluorophenyl)-1 2 3 4-Tetrahydroisoquinoline-3-carboxylate
CAS No.	5937-24-6
Molecular Formula	C18H18FNO2
Molecular Weight	299.34 g/mol
Synonyms	Ethyl 4-(4-fluorophenyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylate; 4-(4-Fluorophenyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic Acid Ethyl Ester; 3-Carbethoxy-4-(4-fluorophenyl)-1,2,3,4-tetrahydroisoquinoline; Ethyl 4-(p-fluorophenyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxylate; 4-(4-Fluorophenyl)-3-(ethoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline; 5937-24-6; SCHEMBL15558427
EINECS	Contact for details

Quality Control

Our Ethyl 4-(4-Fluorophenyl)-1 2 3 4-Tetrahydroisoquinoline-3-carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer requirements for research or cGMP-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorinating agents. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.