Description

(1β,5β)-8-Methyl-8-Azabicyclo[3.2.1]Octane-3α-Carbonitrile is a high-purity, specialized organic intermediate belonging to the tropane alkaloid class. This compound is of significant commercial interest due to its role as a key building block in the synthesis of complex pharmaceutical molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those with tropane-based structures for neurological and other therapeutic applications.
• Agrochemical Research: Used in the research and development of novel pesticides and herbicides, leveraging its complex bicyclic nitrogen-containing scaffold.
• Chemical Synthesis Building Block: Serves as a versatile chiral synthon for constructing more complex molecules in medicinal chemistry and organic synthesis projects.
• Academic & Industrial R&D: Employed in research laboratories for studying structure-activity relationships (SAR) and developing new synthetic methodologies.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(1β,5β)-8-Methyl-8-Azabicyclo[3.2.1]Octane-3α-Carbonitrile
CAS No.	5911-81-9
Molecular Formula	C10H16N2
Molecular Weight	164.25 g/mol
Synonyms	3α-Cyano-8-methyl-8-azabicyclo[3.2.1]octane; 8-Methyl-8-azabicyclo[3.2.1]octane-3-carbonitrile; Tropan-3α-carbonitrile; 3α-Cyanotropane; Nortropine-3α-carbonitrile; 8-Methyl-8-azabicyclo[3.2.1]oct-3α-yl cyanide
EINECS	227-622-7

Quality Control

Our (1β,5β)-8-Methyl-8-Azabicyclo[3.2.1]Octane-3α-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.