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α-Nicotinamideadeninedinucleotide CAS NO 5869-54-5


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CAS No.:5869-54-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

α-Nicotinamideadeninedinucleotide is a critical coenzyme central to cellular energy metabolism and redox reactions. This high-purity biochemical is essential for research and development in life sciences and pharmaceutical manufacturing. It is primarily utilized by biotech companies, academic research institutions, and diagnostic kit manufacturers for enzymatic assays, metabolic studies, and as a key reagent in diagnostic applications.

Application

  • Enzymatic Assay Reagent: A vital cofactor for dehydrogenases in spectrophotometric and fluorometric assays to measure enzyme activity.
  • Biochemical Research: Used in studies of cellular respiration, glycolysis, the citric acid cycle, and other redox-based metabolic pathways.
  • Diagnostic Manufacturing: Incorporated as a core component in clinical diagnostic kits for measuring substrates like glucose, lactate, and ethanol.
  • Pharmaceutical Development: Employed in drug discovery and development for target validation and high-throughput screening assays.
  • Cell Culture & Metabolism Studies: Applied in vitro to investigate mitochondrial function and cellular energy status.
  • Food & Beverage Analysis: Used in enzymatic methods for the quality control and analysis of various food products.

Basic Information

Product Name α-Nicotinamideadeninedinucleotide
CAS No. 5869-54-5
Molecular Formula C21H27N7O14P2
Molecular Weight 663.43 g/mol
Synonyms NAD; β-NAD; Nicotinamide Adenine Dinucleotide (Oxidized Form); Coenzyme I (Oxidized); Diphosphopyridine Nucleotide (DPN+); 1,4-Dihydronicotinamide Adenine Dinucleotide (Oxidized); Adenosine 5'-(trihydrogen diphosphate), 5'-5'-ester with 3-(aminocarbonyl)-1-β-D-ribofuranosylpyridinium, hydroxide, inner salt; Codecarboxylase
EINECS 227-518-6

Quality Control

Our α-Nicotinamideadeninedinucleotide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and diagnostic applications. Certificates of Analysis (COA) detailing purity, absorbance ratios (A260/A280), and other critical parameters are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms
Purity (HPLC) ≥ 95.0%
Absorbance Ratio (A260/A280) 2.0 - 2.3
Water Content (KF) ≤ 5.0%
Biological Activity (Enzymatic Assay) ≥ 90%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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