Description

4-(4-Fluorophenyl)-1H-Pyrazol-5-Amine is a high-purity fluorinated pyrazole derivative, a critical building block in modern organic synthesis. This compound is valued for its role as a versatile intermediate in the development of advanced pharmaceutical and agrochemical agents. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate a fluorinated heterocyclic motif into their target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorophenylpyrazole structure imparts desirable biological activity.
• Material Science Research: Serves as a building block for creating advanced organic materials, such as ligands for catalysts or components in organic electronics.
• Chemical Biology & Proteomics: Employed as a scaffold or tagging agent in the design of molecular probes and biochemical tools.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects requiring high-purity fluorinated heterocycles.

Basic Information

Product Name	4-(4-Fluorophenyl)-1H-Pyrazol-5-Amine
CAS No.	5848-05-5
Molecular Formula	C9H8FN3
Molecular Weight	177.18 g/mol
Synonyms	5-Amino-4-(4-fluorophenyl)-1H-pyrazole; 4-(4-Fluorophenyl)-1H-pyrazol-5-amine; 1H-Pyrazol-5-amine, 4-(4-fluorophenyl)-; 4-(p-Fluorophenyl)-1H-pyrazol-5-amine; 5-Amino-4-(4-fluorophenyl)pyrazole; 4-(4-Fluorophenyl)-5-aminopyrazole; 4-(4-Fluorophenyl)pyrazol-5-amine
EINECS	Contact for details

Quality Control

Our 4-(4-Fluorophenyl)-1H-Pyrazol-5-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.