Description

Mesityllithium CAS NO 5806-59-7 is a highly reactive organolithium compound, specifically a sterically hindered lithium aryl, valued for its powerful basicity and nucleophilicity. It serves as a critical reagent in advanced organic synthesis, enabling the formation of complex carbon-carbon bonds under controlled conditions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and efficient lithiation reactions.

Application

• As a powerful base for the deprotonation of weakly acidic substrates in fine chemical synthesis.
• Key reagent in the preparation of functionalized arenes and heterocycles for pharmaceutical intermediates.
• Used in the synthesis of ligands for catalysis and organometallic complexes.
• Employed in polymer chemistry for the initiation of anionic polymerization to create specialized materials.
• Critical for directed ortho-metalation (DoM) strategies to achieve regioselective functionalization of aromatic rings.
• Utilized in the development of organic electronic materials, such as those used in OLEDs and semiconductors.

Basic Information

Product Name	Mesityllithium
CAS No.	5806-59-7
Molecular Formula	C9H11Li
Molecular Weight	126.12 g/mol
Synonyms	Lithiomesitylene; 2,4,6-Trimethylphenyllithium; Mesityllithium solution; (2,4,6-Trimethylphenyl)lithium; LiMes
EINECS	Contact for details

Quality Control

Our Mesityllithium is produced and handled under stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing assay, impurity profile, and solution concentration. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the exacting standards of research and industrial-scale chemical manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Due to its nature as a highly volatile and pyrophoric organometallic reagent, it must be stored under an inert atmosphere (argon or nitrogen) at temperatures recommended for the specific solvent system, typically between 2°C and 8°C for extended stability. Keep away from heat, sparks, open flames, and moisture. Use only in a certified fume hood with appropriate personal protective equipment.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Identification (NMR)	Conforms to structure
Assay (Titration)	0.5 M to 2.0 M in specified solvent (e.g., cyclohexane/ether)
Purity (GC/HPLC)	≥ 95% (by GC, area %)
Solvent	As specified (e.g., Diethyl ether, Cyclohexane, Toluene)
Base Content	Reported on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.