Description

17,20,21-Trihydroxy-4-Pregnen-3-One is a high-purity steroid derivative, also known as 21-Hydroxyprogesterone, which serves as a critical intermediate in organic synthesis. This compound is valued for its role in the research and development of pharmaceutical actives, particularly in the steroid hormone pathway. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions for synthesizing more complex steroid-based molecules.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of corticosteroid drugs and other steroid-based pharmaceuticals.
• Biochemical Research: Used as a reference standard or reagent in studies investigating steroid metabolism, enzyme activity, and hormonal pathways.
• Fine Chemical Synthesis: Serves as a versatile building block for the custom synthesis of novel steroid analogs and derivatives in contract manufacturing.
• Analytical Standard: Employed in analytical laboratories for method development, calibration, and quality control testing of related steroid compounds.

Basic Information

Product Name	17,20,21-Trihydroxy-4-Pregnen-3-One
CAS No.	5786-59-4
Molecular Formula	C21H32O4
Molecular Weight	348.48 g/mol
Synonyms	21-Hydroxyprogesterone; 17,20,21-Trihydroxypregn-4-en-3-one; 21-Hydroxy-4-pregnene-3,20-dione; 4-Pregnene-17α,20β,21-triol-3-one; 11-Deoxycortisol; Reichstein's Substance S
EINECS	227-324-6

Quality Control

Our 17,20,21-Trihydroxy-4-Pregnen-3-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is kept sealed in a dry environment away from direct light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.