Description

7-Didemethyl Minocycline is a key pharmaceutical intermediate and a structural analog of the broad-spectrum antibiotic minocycline. This compound is of significant interest for its role in the research and development of novel tetracycline-class antibiotics and other therapeutic agents. It serves as a critical building block for medicinal chemists and researchers in the pharmaceutical and biotechnology sectors, enabling the synthesis of new chemical entities with potential antibacterial, anti-inflammatory, or neuroprotective properties.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel tetracycline derivatives and next-generation antibiotics.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to develop new therapeutic compounds.
• Biochemical Research: Employed in studies investigating the mechanism of action of tetracycline-class drugs and bacterial resistance.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Academic & Institutional R&D: Utilized in university and research institute laboratories for exploratory drug discovery projects.

Basic Information

Product Name	7-Didemethyl Minocycline
CAS No.	5679-00-5
Molecular Formula	C₂₁H₂₃N₃O₇
Molecular Weight	429.43 g/mol
Synonyms	7-Dedimethylminocycline; 4,7-Bis(dedimethylamino)minocycline; Minocycline Impurity; 7-Desdimethylminocycline; 7-Didesmethylminocycline; 4,7-Bis-des-dimethyl-minocycline; Tetracycline derivative intermediate
EINECS	Contact for details

Quality Control

Our 7-Didemethyl Minocycline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and pharmaceutical development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.