Description

4-(2,5-Dioxopyrrolidin-1-Yl)-n-(4-Methylphenyl)Benzenesulfonamide is a specialized organic compound featuring a reactive N-hydroxysuccinimide (NHS) ester group linked to a sulfonamide scaffold. This molecular architecture makes it a valuable high-purity intermediate for the synthesis of more complex molecules, particularly in advanced research and development. It is primarily sought after by pharmaceutical and agrochemical R&D teams for creating novel active ingredients and by fine chemical manufacturers producing custom derivatives.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those targeting enzymes where the sulfonamide moiety is pharmacologically active.
• Bioconjugation Reagent: The NHS ester group enables efficient coupling to primary amines, making it useful for labeling proteins, peptides, or other biomolecules in biochemical research.
• Agrochemical Synthesis: Serves as an intermediate in the development of new herbicides, fungicides, or insecticides with tailored properties.
• Material Science Research: Used in the creation of functional polymers or surface coatings where the introduction of a specific sulfonamide group is required.
• Custom Chemical Synthesis: Supplied to fine chemical and CRO (Contract Research Organization) companies for client-specific molecule construction and library development.

Basic Information

Product Name	4-(2,5-Dioxopyrrolidin-1-Yl)-n-(4-Methylphenyl)Benzenesulfonamide
CAS No.	5655-60-7
Molecular Formula	C17H16N2O4S
Molecular Weight	344.39 g/mol
Synonyms	N-(4-Methylphenyl)-4-(2,5-dioxo-1-pyrrolidinyl)benzenesulfonamide; 4-(N-Succinimidyloxycarbonyl)-N-(p-tolyl)benzenesulfonamide; p-Toluenesulfonamide, N-[4-(2,5-dioxo-1-pyrrolidinyl)phenyl]-; 1-{4-[(4-Methylphenyl)sulfamoyl]phenyl}pyrrolidine-2,5-dione; NHS-activated sulfonamide derivative; 5655-60-7; Benzenesulfonamide, 4-(2,5-dioxo-1-pyrrolidinyl)-N-(4-methylphenyl)-
EINECS	Contact for details

Quality Control

Our 4-(2,5-Dioxopyrrolidin-1-Yl)-n-(4-Methylphenyl)Benzenesulfonamide is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high purity and consistent performance as a chemical intermediate. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.