Description

2-Cyclopropyl-2-Hydroxyacetonitrile is a versatile and synthetically valuable nitrile derivative featuring both a hydroxyl and a cyclopropyl functional group. This unique bifunctional structure makes it a critical chiral building block and intermediate in advanced organic synthesis. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the cyclopropyl moiety contributes to biological activity.
• Chiral Auxiliary & Ligand Preparation: Serves as a starting material for synthesizing chiral auxiliaries, ligands for asymmetric catalysis, and other fine chemicals.
• Academic & Industrial R&D: Employed in medicinal chemistry and process chemistry research for method development and novel compound library generation.
• Specialty Chemical Manufacturing: Acts as a building block for high-value performance chemicals, including liquid crystals and advanced materials.

Basic Information

Product Name	2-Cyclopropyl-2-Hydroxyacetonitrile
CAS No.	5648-87-3
Molecular Formula	C5H7NO
Molecular Weight	97.12 g/mol
Synonyms	α-Hydroxycyclopropaneacetonitrile; Cyclopropylglycolonitrile; 2-Hydroxy-2-cyclopropylacetonitrile; (Hydroxycyclopropyl)acetonitrile; 2-Cyclopropyl-2-hydroxyethanenitrile; Glycolonitrile, cyclopropyl-; α-Cyclopropyl-α-hydroxyacetonitrile
EINECS	227-113-7

Quality Control

Our 2-Cyclopropyl-2-Hydroxyacetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.