Description

Z-Dl-Glu-Oh CAS NO 5619-01-2 is a high-purity, non-natural amino acid derivative, specifically the racemic form of pyroglutamic acid. This compound serves as a crucial chiral building block and intermediate in advanced organic synthesis and pharmaceutical research. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries developing novel peptides, active pharmaceutical ingredients (APIs), and biochemical tools.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used as a protected glutamic acid derivative in solid-phase and solution-phase peptide chemistry.
• Biochemical Research: Serves as a precursor or standard in metabolic pathway studies and enzyme inhibition research.
• Asymmetric Synthesis: Employed as a starting material or resolving agent in the preparation of enantiomerically pure compounds.
• Fine Chemical Production: Intermediate for manufacturing specialty chemicals, including flavors, fragrances, and advanced materials.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Item	Detail
Product Name	Z-Dl-Glu-Oh
CAS No.	5619-01-2
Molecular Formula	C₁₃H₁₅NO₅
Molecular Weight	265.26 g/mol
Synonyms	N-Carbobenzoxy-DL-pyroglutamic acid; Z-DL-Pyroglutamic acid; (RS)-1-[(Benzyloxy)carbonyl]-5-oxopyrrolidine-2-carboxylic acid; N-Cbz-DL-pyroglutamic acid; DL-1-(Benzyloxycarbonyl)-5-oxopyrrolidine-2-carboxylic acid; NSC 3349; N-Benzyloxycarbonyl-DL-pyroglutamic acid; DL-2-Pyrrolidone-5-carboxylic acid, N-benzyloxycarbonyl-
EINECS	Contact for details

Quality Control

Our Z-Dl-Glu-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	Racemic mixture (DL, ~50:50)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.