Description

Cyclopropanecarbonitrile, 2-Phenyl-, trans- CAS NO 5590-14-7 is a high-purity, stereochemically defined nitrile derivative featuring a phenyl-substituted cyclopropane ring. This compound serves as a versatile and valuable chiral building block in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS and cardiovascular diseases.
• Agrochemical Synthesis: Used in the preparation of advanced pesticide and herbicide candidates, leveraging the rigid cyclopropane scaffold for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty monomers and polymers with unique structural properties.
• Academic & Contract Research: A critical reagent for methodological studies in organic chemistry, including cycloaddition and ring-opening reactions.
• Fine Chemical Production: Used in the custom synthesis of complex, high-value molecules for various technological applications.

Basic Information

Product Name	Cyclopropanecarbonitrile, 2-Phenyl-, trans-
CAS No.	5590-14-7
Molecular Formula	C10H9N
Molecular Weight	143.19 g/mol
Synonyms	trans-2-Phenylcyclopropanecarbonitrile; (1R,2S)-rel-2-Phenylcyclopropanecarbonitrile; (1S,2R)-rel-2-Phenylcyclopropanecarbonitrile; 2-Phenylcyclopropanecarbonitrile, trans-; (±)-trans-2-Phenylcyclopropanecarbonitrile; rac-trans-2-Phenylcyclopropanecarbonitrile; trans-2-Phenylcyclopropanenitrile
EINECS	Contact for details

Quality Control

Our Cyclopropanecarbonitrile, 2-Phenyl-, trans- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and process chemistry. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profile is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% trans-isomer
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.