Description

Cefalonium Hydrate is a first-generation cephalosporin antibiotic. This compound is valued for its bactericidal activity against a range of Gram-positive and some Gram-negative bacteria. It is primarily utilized in the pharmaceutical industry for the research and development of antimicrobial agents. Cefalonium Hydrate CAS NO 5575-21-3 serves as a critical intermediate and reference standard in analytical and synthetic chemistry.

Application

• Pharmaceutical Intermediate: Key starting material in the synthesis of cephalosporin-based antibiotic formulations.
• Reference Standard: Used in analytical laboratories for quality control, method validation, and calibration in HPLC, LC-MS, and other chromatographic systems.
• Microbiological Research: Employed in studies to understand bacterial resistance mechanisms and evaluate the efficacy of antimicrobial compounds.
• Veterinary Medicine: Investigated for potential applications in treating bacterial infections in animals.
• Active Pharmaceutical Ingredient (API) Development: Serves as the core active component in the development of new antibiotic drugs.

Basic Information

Item	Details
Product Name	Cefalonium Hydrate
CAS No.	5575-21-3
Molecular Formula	C20H20N4O5S2 • xH2O
Molecular Weight	476.53 g/mol (anhydrous basis)
Synonyms	7-[(2-Thienylacetyl)amino]-3-[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrate; Cephalonium Hydrate; Cephazolin C; Antibiotic C 43; Antibiotic 43; SQ 14,359
EINECS	Contact for details

Quality Control

Our Cefalonium Hydrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and potency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing results from tests including HPLC assay, related substances, water content, and residual solvents. The product is suitable for use as a pharmaceutical reference standard.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.