Description

For-Ser(Bzl)-Oh is a protected serine derivative, specifically the benzyl ester of L-serine, widely used as a crucial building block in peptide synthesis. Its primary value lies in providing a reactive carboxyl group while protecting the serine side chain hydroxyl, enabling precise and efficient construction of complex peptide sequences. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries developing therapeutic peptides, diagnostic agents, and novel bioactive compounds.

Application

• Solid-Phase Peptide Synthesis (SPPS): A fundamental protected amino acid for the automated, sequential assembly of peptide chains.
• Solution-Phase Peptide Synthesis: Used in classical coupling reactions for the production of specific peptide fragments and small peptides.
• Pharmaceutical Intermediate: Serves as a key raw material in the research and development of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Bioconjugation and Labeling: The reactive ester group can be utilized for attaching peptides to other molecules, surfaces, or reporter tags.
• Biochemical Research: Employed in studying enzyme mechanisms, protein-protein interactions, and structure-activity relationships (SAR).
• Production of Custom Peptides: Used by CROs and CDMOs to synthesize bespoke peptides for client research and pre-clinical studies.

Basic Information

Product Name	For-Ser(Bzl)-Oh
CAS No.	5513-74-6
Molecular Formula	C10H13NO3
Molecular Weight	195.22 g/mol
Synonyms	L-Serine, benzyl ester; H-Ser(Bzl)-OH; Benzyl L-serinate; (S)-2-Amino-3-hydroxypropanoic acid benzyl ester; Serine benzyl ester; N-Deprotected Serine benzyl ester; Fmoc-Ser(Bzl)-OH precursor; Boc-Ser(Bzl)-OH precursor
EINECS	226-848-8

Quality Control

Our For-Ser(Bzl)-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for sensitive applications like peptide synthesis. Each lot is subjected to comprehensive analytical testing, including HPLC for purity and chiral integrity, and is supplied with a detailed Certificate of Analysis (COA). We adhere to cGMP principles where applicable to support our clients' regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation [α]	+14.0° to +16.0° (c=1 in H2O)
Melting Point	Approx. 220-225°C (dec.)
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.