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2-([(Benzyloxy)Carbonyl]Amino)-2-Phenylacetic Acid CAS NO 5491-18-9


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CAS No.:5491-18-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-([(Benzyloxy)Carbonyl]Amino)-2-Phenylacetic Acid is a high-purity, protected amino acid derivative widely used as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring precise molecular control in the development of complex molecules. It is primarily utilized in the pharmaceutical industry for peptide synthesis and as a key intermediate in the production of active pharmaceutical ingredients (APIs) and fine chemicals.

Application

  • Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
  • Peptide Synthesis: Serves as a protected amino acid derivative (N-Cbz-protected phenylglycine) in solid-phase and solution-phase peptide chemistry.
  • Chemical Research & Development: Used as a versatile building block in medicinal chemistry for creating novel compound libraries and exploring structure-activity relationships (SAR).
  • Fine Chemical Production: An intermediate in the manufacture of specialty chemicals, catalysts, and ligands for asymmetric synthesis.
  • Bioconjugation: Potential use in the development of antibody-drug conjugates (ADCs) and other bioconjugate platforms.
  • Academic Research: Employed in university and institutional labs for teaching advanced organic synthesis techniques and methodology development.

Basic Information

Product Name 2-([(Benzyloxy)Carbonyl]Amino)-2-Phenylacetic Acid
CAS No. 5491-18-9
Molecular Formula C16H15NO4
Molecular Weight 285.29 g/mol
Synonyms N-Carbobenzyloxy-DL-phenylglycine; N-Cbz-DL-phenylglycine; (RS)-2-[(Benzyloxycarbonyl)amino]-2-phenylacetic acid; DL-N-Carbobenzoxyphenylglycine; Z-DL-Phenylglycine; NSC 3349; (2RS)-2-[(Phenylmethoxy)carbonyl]amino]-2-phenylacetic acid; N-Benzyloxycarbonyl-DL-phenylglycine
EINECS 226-834-8

Quality Control

Our 2-([(Benzyloxy)Carbonyl]Amino)-2-Phenylacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D and fine chemical synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥98.0%
Melting Point 158°C - 165°C
Loss on Drying ≤0.5%
Heavy Metals ≤20 ppm
Residue on Ignition ≤0.1%
Optical Rotation Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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