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2-([(Benzyloxy)Carbonyl]Amino)-2-Phenylacetic Acid CAS NO 5491-18-9
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CAS No.:5491-18-9
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-([(Benzyloxy)Carbonyl]Amino)-2-Phenylacetic Acid is a high-purity, protected amino acid derivative widely used as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring precise molecular control in the development of complex molecules. It is primarily utilized in the pharmaceutical industry for peptide synthesis and as a key intermediate in the production of active pharmaceutical ingredients (APIs) and fine chemicals.
Application
- Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
- Peptide Synthesis: Serves as a protected amino acid derivative (N-Cbz-protected phenylglycine) in solid-phase and solution-phase peptide chemistry.
- Chemical Research & Development: Used as a versatile building block in medicinal chemistry for creating novel compound libraries and exploring structure-activity relationships (SAR).
- Fine Chemical Production: An intermediate in the manufacture of specialty chemicals, catalysts, and ligands for asymmetric synthesis.
- Bioconjugation: Potential use in the development of antibody-drug conjugates (ADCs) and other bioconjugate platforms.
- Academic Research: Employed in university and institutional labs for teaching advanced organic synthesis techniques and methodology development.
Basic Information
| Product Name | 2-([(Benzyloxy)Carbonyl]Amino)-2-Phenylacetic Acid |
| CAS No. | 5491-18-9 |
| Molecular Formula | C16H15NO4 |
| Molecular Weight | 285.29 g/mol |
| Synonyms | N-Carbobenzyloxy-DL-phenylglycine; N-Cbz-DL-phenylglycine; (RS)-2-[(Benzyloxycarbonyl)amino]-2-phenylacetic acid; DL-N-Carbobenzoxyphenylglycine; Z-DL-Phenylglycine; NSC 3349; (2RS)-2-[(Phenylmethoxy)carbonyl]amino]-2-phenylacetic acid; N-Benzyloxycarbonyl-DL-phenylglycine |
| EINECS | 226-834-8 |
Quality Control
Our 2-([(Benzyloxy)Carbonyl]Amino)-2-Phenylacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D and fine chemical synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Assay (HPLC) | ≥98.0% |
| Melting Point | 158°C - 165°C |
| Loss on Drying | ≤0.5% |
| Heavy Metals | ≤20 ppm |
| Residue on Ignition | ≤0.1% |
| Optical Rotation | Contact for details |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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