Description

2-(Trifluoroacetamido)Ethylamine Hydrochloride is a high-purity trifluoroacetyl-protected amine derivative, essential for advanced organic synthesis and pharmaceutical research. Its primary value lies in serving as a versatile and reactive building block for introducing the ethylamine moiety under controlled conditions. This compound is particularly critical for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a protected amine functional group.
• Peptide Synthesis: Used in the preparation of modified peptides and peptidomimetics, where the trifluoroacetamido group acts as a protective group for amines.
• Agrochemical Research: Serves as a precursor in the development of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for metal catalysis and organocatalysts.
• Bioconjugation Chemistry: Useful in linker chemistry for attaching molecules to biomolecules like proteins or antibodies.
• Material Science: Acts as a monomer or modifier in the synthesis of specialty polymers and functional materials.

Basic Information

Product Name	2-(Trifluoroacetamido)Ethylamine Hydrochloride
CAS No.	5458-14-0
Molecular Formula	C4H8ClF3N2O
Molecular Weight	192.57 g/mol
Synonyms	N-(2-Aminoethyl)-2,2,2-trifluoroacetamide hydrochloride; 2,2,2-Trifluoro-N-(2-aminoethyl)acetamide hydrochloride; Trifluoroacetamidoethylamine HCl; 2-Aminoethyltrifluoroacetamide hydrochloride; TFAEA-HCl; N1-(2,2,2-Trifluoroacetyl)ethylenediamine hydrochloride; Ethylenediamine, N-(trifluoroacetyl)-, monohydrochloride
EINECS	226-704-8

Quality Control

Our 2-(Trifluoroacetamido)Ethylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.