Description

2-[(2-Iodoacetyl)Amino]-3-Phenyl-Propanoic Acid is a specialized iodoacetamide derivative used as a key biochemical reagent. This compound is valued for its role as an alkylating agent, specifically targeting cysteine residues in peptides and proteins. It is primarily utilized by researchers and manufacturers in the fields of bioconjugation, proteomics, and pharmaceutical intermediate synthesis. The product is supplied to ensure high purity and reactivity for critical applications in life science research and development.

Application

• Bioconjugation Reagent: For site-specific modification of cysteine-containing proteins and peptides.
• Proteomics Research: As a tool for protein structure-function studies and activity-based protein profiling (ABPP).
• Pharmaceutical Intermediate: In the synthesis of targeted therapeutics and drug candidates.
• Enzyme Inhibitor Studies: For investigating enzyme active sites that contain critical cysteine residues.
• Crosslinking Agent: Used in the preparation of affinity matrices and immobilized ligands for chromatography.
• Chemical Biology Probes: For labeling and tracking biomolecules in complex biological systems.

Basic Information

Product Name	2-[(2-Iodoacetyl)Amino]-3-Phenyl-Propanoic Acid
CAS No.	5419-43-2
Molecular Formula	C11H12INO3
Molecular Weight	333.12 g/mol
Synonyms	N-(Iodoacetyl)-L-phenylalanine; Iodoacetamido-L-phenylalanine; L-Phenylalanine, N-(iodoacetyl)-; (S)-2-(2-Iodoacetamido)-3-phenylpropanoic acid; Iodoacetylphenylalanine; 2-(2-Iodoacetamido)-3-phenylpropionic acid; N-Iodoacetyl-L-phenylalanine; Iodoacetamide-Phe-OH
EINECS	Contact for details

Quality Control

Our 2-[(2-Iodoacetyl)Amino]-3-Phenyl-Propanoic Acid is manufactured under controlled conditions to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes rigorous analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and specific tests for heavy metals and residual solvents. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	-15° to -25° (c=1 in DMF)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.