Description

4-Pentyn-1-ol is a terminal alkyne bearing a primary hydroxyl group, making it a versatile bifunctional building block in organic synthesis. This compound matters for its ability to participate in click chemistry reactions, such as the copper-catalyzed azide-alkyne cycloaddition (CuAAC), and other catalytic transformations to create complex molecular architectures. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing active ingredients, polymers, and specialty chemicals.

Application

• Pharmaceutical Intermediates: Serves as a key synthon for constructing bioactive molecules, heterocycles, and potential drug candidates via alkyne-based coupling reactions.
• Polymer & Material Science: Used as a monomer or cross-linking agent in the synthesis of specialty polymers, dendrimers, and functionalized surfaces.
• Agrochemical Synthesis: Employed in the research and development of novel pesticides, herbicides, and plant growth regulators.
• Click Chemistry: An ideal substrate for Huisgen cycloaddition reactions to create 1,2,3-triazoles, a privileged scaffold in medicinal chemistry.
• Ligand & Catalyst Development: Utilized in the preparation of specialized ligands for transition metal catalysis.
• Organic Synthesis Building Block: Functions in Sonogashira coupling, hydroalkynylation, and other C-C bond forming reactions to extend carbon chains.
• Chemical Probes & Diagnostics: Can be tagged with fluorescent or reporter groups for biochemical labeling and imaging applications.

Basic Information

Product Name	4-Pentyn-1-ol
CAS No.	5390-04-5
Molecular Formula	C5H8O
Molecular Weight	84.12 g/mol
Synonyms	4-Pentyn-1-ol; 4-Pentynol; 1-Hydroxy-4-pentyne; 4-Pentyne-1-ol; Pent-4-yn-1-ol; 4-Pentynyl alcohol; But-2-ynylcarbinol; 2-Butyn-1-ylcarbinol
EINECS	226-382-7

Quality Control

Our 4-Pentyn-1-ol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat, sparks, and open flame. Due to its highly volatile nature, keep container tightly sealed when not in use. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.