Description

N-[4-(Aminosulfonyl)Phenyl]-2-Bromoacetamide is a specialized bromoacetamide derivative featuring a sulfonamide functional group, making it a valuable building block in synthetic organic chemistry. This compound is particularly significant for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily sought after by research institutions, pharmaceutical development labs, and fine chemical manufacturers engaged in sulfonamide-based drug discovery and the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of sulfonamide-containing drug candidates, including potential diuretics, carbonic anhydrase inhibitors, and antimicrobial agents.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and fungicides where the sulfonamide moiety is integral to biological activity.
• Bioconjugation & Protein Modification: The reactive bromoacetyl group allows for selective alkylation of thiol groups in peptides and proteins, useful in bioconjugation chemistry and probe development.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialized polymers and functional materials.
• Chemical Biology Tool: Employed in the design and synthesis of activity-based probes (ABPs) for studying enzyme function and mechanism.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	N-[4-(Aminosulfonyl)Phenyl]-2-Bromoacetamide
CAS No.	5332-70-7
Molecular Formula	C8H9BrN2O3S
Molecular Weight	293.14 g/mol
Synonyms	2-Bromo-N-(4-sulfamoylphenyl)acetamide; 4'-(Bromoacetamido)benzenesulfonamide; p-Sulfamoyl-α-bromoacetanilide; N-(4-Sulfamoylphenyl)bromoacetamide; Bromoacetic acid 4-sulfamoylanilide; 5332-70-7; 4-Acetamidobenzenesulfonamide, 2-bromo-; α-Bromo-4-sulfamoylacetanilide
EINECS	Contact for details

Quality Control

Our N-[4-(Aminosulfonyl)Phenyl]-2-Bromoacetamide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of our pharmaceutical and fine chemical partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.