Description

1-Methyl n-[n-[n-[n-[(tert-Butoxy)Carbonyl]-L-Tryptophyl]-L-Methionyl]-L-α-Aspartyl]-3-Phenyl-L-Alaninate is a protected peptide derivative of significant importance in advanced pharmaceutical research and development. This compound serves as a critical building block for the synthesis of complex peptides and peptidomimetics, offering precise control over molecular structure. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, particularly for developing therapeutic agents targeting neurological and metabolic pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel peptide-based active pharmaceutical ingredients (APIs).
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Peptide Synthesis: Serves as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis (SPPS).
• Bioconjugation: Employed in the development of peptide-drug conjugates and other bioconjugate molecules.
• Biochemical Research: Utilized as a tool compound in enzymatic studies and proteomics research.
• Reference Standard: Acts as a high-purity analytical standard for quality control in peptide manufacturing.

Basic Information

Product Name	1-Methyl n-[n-[n-[n-[(tert-Butoxy)Carbonyl]-L-Tryptophyl]-L-Methionyl]-L-α-Aspartyl]-3-Phenyl-L-Alaninate
CAS No.	5262-09-9
Molecular Formula	C41H53N7O9S
Molecular Weight	820.0 g/mol
Synonyms	Boc-Trp-Met-Asp-Phe-OMe; Boc-L-Tryptophyl-L-Methionyl-L-α-Aspartyl-3-Phenyl-L-Alanine Methyl Ester; 1-Methyl N-[N-[N-[N-[(1,1-Dimethylethoxy)carbonyl]-L-tryptophyl]-L-methionyl]-L-α-aspartyl]-3-phenyl-L-alaninate; Boc-Trp-Met-Asp-Phe Methyl Ester; (S)-Methyl 2-((S)-2-((S)-2-((S)-2-((tert-butoxycarbonyl)amino)-3-(1H-indol-3-yl)propanamido)-4-(methylthio)butanamido)-3-carboxypropanamido)-3-phenylpropanoate; Protected Pentapeptide Ester; CAS 5262-09-9
EINECS	Contact for details

Quality Control

Our 1-Methyl n-[n-[n-[n-[(tert-Butoxy)Carbonyl]-L-Tryptophyl]-L-Methionyl]-L-α-Aspartyl]-3-Phenyl-L-Alaninate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.