Description

Ethyl 2,2,3,4,4,4-Hexafluorobutyrate is a high-purity fluorinated ester compound, serving as a versatile building block and intermediate in advanced chemical synthesis. Its value lies in the unique reactivity and properties imparted by the hexafluorobutyl group, enabling the development of materials with enhanced stability and performance. This product is essential for R&D and production in the pharmaceutical, agrochemical, and specialty polymer industries, where precise fluorination is required.

Application

• Pharmaceutical Intermediate: A key synthon for introducing fluorinated moieties into active pharmaceutical ingredients (APIs) to modulate bioavailability, metabolic stability, and lipophilicity.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where fluorine atoms enhance biological activity and environmental persistence.
• Fluorinated Polymer & Material Science: Acts as a monomer or modifier in the synthesis of specialty polymers, coatings, and elastomers to improve chemical resistance, thermal stability, and surface properties.
• Liquid Crystal & Electronic Chemicals: Employed in the manufacture of fluorinated liquid crystals and dielectric fluids for display technologies and electronic applications.
• Organic Synthesis & Catalysis: Serves as a fluorinated alkylating agent or a precursor for other hexafluorobutyl-containing reagents in complex organic transformations.
• Surface Active Agents & Fluorosurfactants: A precursor for synthesizing fluorinated surfactants and surface modifiers that provide exceptional wetting and leveling properties.

Basic Information

Item	Details
Product Name	Ethyl 2,2,3,4,4,4-Hexafluorobutyrate
CAS No.	5200-38-4
Molecular Formula	C6H6F6O2
Molecular Weight	224.10 g/mol
Synonyms	Ethyl Hexafluorobutyrate; 2,2,3,4,4,4-Hexafluorobutanoic Acid Ethyl Ester; Ethyl Perfluorobutyrate; Ethyl 4,4,4-Trifluoro-3-(trifluoromethyl)butyrate; NSC 9235; Butanoic acid, 2,2,3,4,4,4-hexafluoro-, ethyl ester; Ethyl α,β,β-Trifluoro-β-(trifluoromethyl)butyrate
EINECS	Contact for details

Quality Control

Our Ethyl 2,2,3,4,4,4-Hexafluorobutyrate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including GC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided and available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and sources of ignition. Due to its fluoride/strong alkali reactivity profile, ensure segregation from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.320 - 1.340
Density (20°C)	1.40 - 1.50 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.