Description

1-Chloro-2,3,4,6-Tetrafluorobenzene is a versatile fluorinated aromatic building block, valued for its unique combination of halogen and fluorine substituents which impart significant chemical stability and reactivity. This compound is essential for the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its structure serves as a key intermediate. It is primarily sought after by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug molecules, particularly those requiring fluorinated aromatic cores for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of modern pesticides and herbicides, where the fluorine atoms contribute to improved efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials, contributing to their thermal stability and electronic properties.
• Organic Synthesis & Catalysis: Employed in cross-coupling reactions and as a ligand precursor in organometallic chemistry due to its electron-deficient aromatic ring.
• Polymer Modification: Used to introduce fluorine-containing side chains into polymers, enhancing their chemical resistance, thermal stability, and surface properties.

Basic Information

Product Name	1-Chloro-2,3,4,6-Tetrafluorobenzene
CAS No.	5172-06-5
Molecular Formula	C6HClF4
Molecular Weight	184.52 g/mol
Synonyms	2,3,4,6-Tetrafluoro-1-chlorobenzene; 1-Chloro-2,3,4,6-tetrafluorobenzene; Benzene, 1-chloro-2,3,4,6-tetrafluoro-; 2,3,4,6-Tetrafluorochlorobenzene; p-Chlorotetrafluorobenzene; 1-Chloro-perfluorobenzene (partial); NSC 9235
EINECS	225-935-9

Quality Control

Every batch of 1-Chloro-2,3,4,6-Tetrafluorobenzene is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by GC, HPLC, and NMR is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is 2-25°C. The container must be kept tightly sealed in a dry environment to prevent moisture ingress.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%
Density (at 20°C)	~1.6 g/mL
Refractive Index (n20D)	~1.45

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.