Description

1-(3-Dimethylaminopropyl)-1H-Pyrrole-2,5-Dione is a versatile heterocyclic building block and reactive intermediate of significant interest in advanced organic synthesis. Its value lies in its bifunctional structure, featuring both a reactive pyrrole-2,5-dione (maleimide) moiety and a tertiary amine group, enabling its use in the creation of complex molecular architectures. This compound is primarily needed by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and polymer sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring maleimide-based conjugation or amine-functionalized heterocycles.
• Bioconjugation Reagent: Used for labeling proteins, antibodies, and peptides via Michael addition to thiol groups, facilitating the development of diagnostics and antibody-drug conjugates (ADCs).
• Polymer Chemistry: Serves as a functional monomer or cross-linking agent in the production of specialty polymers, coatings, and hydrogels with tailored properties.
• Agrochemical Synthesis: Employed as a building block for creating novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Utilized in the development of advanced organic electronic materials, dyes, and photoactive compounds.
• Chemical Biology Probes: Acts as a scaffold for designing activity-based probes and inhibitors to study enzyme function and biological pathways.

Basic Information

Product Name	1-(3-Dimethylaminopropyl)-1H-Pyrrole-2,5-Dione
CAS No.	5135-54-6
Molecular Formula	C9H14N2O2
Molecular Weight	182.22 g/mol
Synonyms	N-(3-Dimethylaminopropyl)maleimide; 1H-Pyrrole-2,5-dione, 1-(3-(dimethylamino)propyl)-; 3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N,N-dimethylpropan-1-amine; Maleimide, N-(3-dimethylaminopropyl)-; N-Maleimidopropyl-N',N'-dimethylamine; DMAP-Maleimide; 1-(3-Dimethylaminopropyl)maleimide
EINECS	Contact for details

Quality Control

Our 1-(3-Dimethylaminopropyl)-1H-Pyrrole-2,5-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets high-purity standards suitable for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation by atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.