Description

Prochlorperazine Mesylate is a high-purity pharmaceutical salt form of the potent phenothiazine derivative, prochlorperazine. This compound is a critical active pharmaceutical ingredient (API) valued for its reliable antiemetic and antipsychotic properties. It is primarily utilized by pharmaceutical manufacturers and research institutions in the formulation of injectable and oral dosage forms. Our supply ensures consistent quality and stability, meeting the stringent demands of global regulatory standards.

Application

• Pharmaceutical API: Primary use as the active ingredient in antiemetic and antipsychotic medications.
• Injectable Formulations: Key component in sterile injectable solutions for rapid control of severe nausea, vomiting, and vertigo.
• Oral Solid Dosage: Used in the production of tablets and capsules for the management of psychotic disorders and nausea.
• Neurological Research: A reference standard and tool compound in studies of dopamine D2 receptor antagonism.
• Veterinary Medicine: Potential application in veterinary pharmaceuticals for antiemetic purposes.
• Chemical Synthesis: Serves as a key intermediate or reference material for the synthesis of related phenothiazine derivatives.

Basic Information

Product Name	Prochlorperazine Mesylate
CAS No.	5132-55-8
Molecular Formula	C₂₀H₂₄ClN₃S • CH₄O₃S
Molecular Weight	489.05 g/mol
Synonyms	Prochlorperazine Methanesulfonate; Compazine Mesylate; 2-Chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine Methanesulfonate; NSC 77625; Prochlorperazine Monomethanesulfonate; Prochlorpemazine Mesilate; Prochlorperazine Mesilate
EINECS	225-881-6

Quality Control

Our Prochlorperazine Mesylate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for assay and impurity profiling, to ensure it meets high-purity pharmacopeial standards. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specifications for identity, purity, and related substances. We support audits and can provide documentation for regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity: ≤ 0.5%; Total impurities: ≤ 1.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.