Description

n-Phthaloyl-L-Phenylalanine is a high-purity, protected amino acid derivative primarily used as a critical chiral building block in advanced organic synthesis. This compound is essential for ensuring stereochemical integrity and high yields in the production of complex peptides and pharmaceutical intermediates. It is particularly valuable for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality raw materials for API development and process chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis as a protected phenylalanine derivative to prevent racemization.
• Asymmetric Synthesis: Serves as a starting material or auxiliary in asymmetric catalytic reactions and the preparation of non-natural amino acids.
• Biochemical Research: Employed in proteomics research, enzyme substrate studies, and the development of enzyme inhibitors.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals, including flavors, fragrances, and advanced materials.
• Academic & R&D: A standard reagent in university and corporate research laboratories for method development and discovery chemistry.

Basic Information

Product Name	n-Phthaloyl-L-Phenylalanine
CAS No.	5123-55-7
Molecular Formula	C17H13NO4
Molecular Weight	295.29 g/mol
Synonyms	N-Phthaloyl-L-phenylalanine; (S)-2-(1,3-Dioxoisoindolin-2-yl)-3-phenylpropanoic acid; L-Phenylalanine, N-phthaloyl-; Phth-Phe-OH; 2-[(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)carbonyl]amino]-3-phenylpropanoic acid; N-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-L-phenylalanine; Phthaloylphenylalanine
EINECS	225-863-7

Quality Control

Our n-Phthaloyl-L-Phenylalanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm enantiomeric excess, and identity confirmation via IR and NMR spectroscopy. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.