Description

1-Ethynyl-2,3,4,5,6-Pentafluoro-Benzene is a highly fluorinated aromatic alkyne building block of significant interest in advanced organic synthesis. Its unique structure, featuring a reactive ethynyl group on a perfluorinated benzene ring, makes it a critical precursor for creating complex molecules with tailored electronic and physical properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to develop novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, potentially enhancing metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in creating novel fluorinated pesticides and herbicides, where fluorine atoms can improve efficacy and environmental profile.
• Advanced Material Precursor: Serves as a monomer or cross-linker in the synthesis of specialty polymers, liquid crystals, and organic electronic materials.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create sophisticated ligands for catalysis and material science applications.
• Fluorine Chemistry Research: A valuable tool in academic and industrial R&D for studying perfluoroaryl substitution reactions and alkyne transformations.
• Surface Modification Agent: Can be used to introduce hydrophobic, oleophobic, and chemically resistant perfluorinated aromatic groups onto surfaces.

Basic Information

Product Name	1-Ethynyl-2,3,4,5,6-Pentafluoro-Benzene
CAS No.	5122-07-6
Molecular Formula	C8HF5
Molecular Weight	192.09 g/mol
Synonyms	Pentafluorophenylacetylene; Ethynylpentafluorobenzene; 2,3,4,5,6-Pentafluorophenylacetylene; Perfluorophenylacetylene; (Pentafluorophenyl)ethyne; C6F5C≡CH; 1-Ethynylpentafluorobenzene; PFP-acetylene
EINECS	Contact for details

Quality Control

Our 1-Ethynyl-2,3,4,5,6-Pentafluoro-Benzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed when not in use and stored away from heat sources and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.