Description

4-o-(2,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranosyl)-D-Glucononitrile 2,3,5,6-Tetraacetate is a key, highly functionalized carbohydrate derivative and a crucial protected intermediate in synthetic organic chemistry. Its value lies in providing a reactive nitrile group and multiple acetyl protecting groups, enabling precise, multi-step synthesis of complex sugar-based molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries developing novel glycosides, nucleoside analogs, and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel glycosidase inhibitors, antiviral agents, and other carbohydrate-based therapeutics.
• Glycochemistry Research: Serves as a versatile precursor for the controlled synthesis of complex oligosaccharides, glycoconjugates, and glycomimetics in academic and industrial R&D.
• Nucleoside Analog Synthesis: Used in the preparation of modified nucleosides with potential applications as anticancer or antiviral drugs.
• Fine Chemical Production: Acts as a chiral synthon for the asymmetric synthesis of natural products and specialty chemicals requiring specific sugar motifs.
• Bioconjugation Chemistry: The reactive nitrile functionality can be utilized for linking carbohydrate moieties to proteins, peptides, or other biomolecules.
• Reference Standard: Employed as a high-purity analytical standard for method development and quality control in related synthetic processes.

Basic Information

Item	Details
Product Name	4-o-(2,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranosyl)-D-Glucononitrile 2,3,5,6-Tetraacetate
CAS No.	5120-84-3
Molecular Formula	C27H35NO17
Molecular Weight	645.57 g/mol
Synonyms	D-Glucononitrile, 4-O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-, 2,3,5,6-tetraacetate; 2,3,5,6-Tetra-O-acetyl-4-O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-D-glucononitrile; Peracetylated Glucononitrile Glucoside; Tetraacetyl Glucononitrile Glucoside Tetraacetate; 1-Cyano-1-deoxy-4-O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-D-glucitol 2,3,5,6-tetraacetate; Acetylated Cyanohydrin Glucoside
EINECS	Contact for details

Quality Control

Our 4-o-(2,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranosyl)-D-Glucononitrile 2,3,5,6-Tetraacetate is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for demanding synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with cGMP and ISO standards for pharmaceutical intermediates, and specifications can be tailored to meet specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions; consider storage with desiccant in a sealed container. For long-term stability, store under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.