Description

2'-Hydroxymethaqualone is a significant chemical intermediate and reference standard within the pharmaceutical research and development sector. Its value lies in its role as a key synthon for the preparation of more complex quinazolinone derivatives, which are of high interest in medicinal chemistry. This compound is primarily needed by R&D laboratories, analytical service providers, and fine chemical manufacturers serving the pharmaceutical and life sciences industries.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel quinazolinone-based active pharmaceutical ingredients (APIs) and drug candidates.
• Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical testing.
• Metabolite Studies: Employed in pharmacokinetic and metabolic pathway research for related pharmaceutical compounds.
• Chemical Research: Utilized in academic and industrial research for exploring structure-activity relationships (SAR) and developing new heterocyclic compounds.
• Impurity Standard: Acts as a specified impurity standard to ensure the purity and safety profile of related pharmaceutical products during manufacturing.

Basic Information

Product Name	2'-Hydroxymethaqualone
CAS No.	5060-50-4
Molecular Formula	C₁₇H₁₄N₂O₂
Molecular Weight	278.31 g/mol
Synonyms	2'-Hydroxy-2-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone; 2-Methyl-3-(o-tolyl)-4(3H)-quinazolinone-2'-ol; 3-(2-Methylphenyl)-2-methyl-4(3H)-quinazolinone-2'-ol; Methaqualone metabolite 2'-hydroxy; 2'-OH-Methaqualone
EINECS	Contact for details

Quality Control

Our 2'-Hydroxymethaqualone is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and pharmaceutical intermediate standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.