Description

1-(3'-Fluoro-Biphenyl-4-Yl)-Ethanone is a high-purity fluorinated aromatic ketone, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in the precise introduction of both a biphenyl scaffold and a ketone functional group, enabling the construction of complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and fungicides, where the fluorine atom enhances biological activity and stability.
• Liquid Crystal & OLED Material Precursor: Serves as a core structure in the manufacture of fluorinated compounds for electronic display and lighting applications.
• Organic Light-Emitting Diode (OLED) Research: Acts as an intermediate for electron-transport materials or host materials in emissive layers.
• Chemical Research & Development: A versatile reagent for Suzuki-Miyaura and other cross-coupling reactions to create extended conjugated systems.
• Fluorine Chemistry Studies: Used as a model compound to study the effects of fluorine substitution on the reactivity and properties of biphenyl systems.

Basic Information

Product Name	1-(3'-Fluoro-Biphenyl-4-Yl)-Ethanone
CAS No.	5002-42-6
Molecular Formula	C14H11FO
Molecular Weight	214.24 g/mol
Synonyms	3'-Fluoro-4-acetylbiphenyl; 4-Acetyl-3'-fluorobiphenyl; 1-(3'-Fluorobiphenyl-4-yl)ethanone; 1-(4-Biphenylyl)-2-fluoroethanone (incorrect but common); 3-Fluorobiphenyl-4-yl methyl ketone; 4-Acetyl-3'-fluoro-1,1'-biphenyl; 3'-Fluoro-[1,1'-biphenyl]-4-yl ethanone
EINECS	Contact for details

Quality Control

Our 1-(3'-Fluoro-Biphenyl-4-Yl)-Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.