Description

Ethyl 2'-Fluoro-4-Biphenylylacetate is a high-purity fluorinated biphenyl derivative, a key intermediate in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and specialty materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries seeking to incorporate fluorinated biphenyl motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, especially non-steroidal anti-inflammatory drugs (NSAIDs) and other bioactive molecules containing a fluorinated biphenyl core.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, where the fluorine atom can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated mesogens and charge-transport materials, contributing to improved performance in display and lighting technologies.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, ester hydrolysis, and subsequent functional group transformations to create diverse chemical libraries.
• Chemical Reference Standard: Used as a high-purity analytical standard for quality control and method development in pharmaceutical and chemical analysis.

Basic Information

Product Name	Ethyl 2'-Fluoro-4-Biphenylylacetate
CAS No.	5002-30-2
Molecular Formula	C₁₆H₁₅FO₂
Molecular Weight	258.29 g/mol
Synonyms	Ethyl (2'-Fluoro[1,1'-biphenyl]-4-yl)acetate; 2'-Fluoro-4-biphenylylacetic Acid Ethyl Ester; [1,1'-Biphenyl]-4-acetic acid, 2'-fluoro-, ethyl ester; Ethyl 2-Fluorobiphenyl-4-ylacetate; 4-Biphenylylacetic acid, 2'-fluoro-, ethyl ester; Ethyl (2-fluorobiphenyl-4-yl)acetate; NSC 334365
EINECS	Contact for details

Quality Control

Our Ethyl 2'-Fluoro-4-Biphenylylacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications in cGMP environments and research requiring the highest standards of material integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Store away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single unknown impurity	≤0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.