Description

sec-Butyllithium is a highly reactive organolithium compound widely used as a powerful initiator and strong base in synthetic chemistry. Its precise control over polymerization and metalation reactions makes it a critical reagent for producing high-performance materials and complex organic molecules. This product is essential for R&D and manufacturing in the pharmaceutical, advanced polymer, and specialty chemical industries.

Application

• Anionic Polymerization Initiator: Primary use for the synthesis of styrenic block copolymers (SBCs), polybutadiene, and other specialty elastomers with controlled molecular weight and microstructure.
• Organic Synthesis Reagent: Acts as a strong base for deprotonation and metal-halogen exchange reactions to generate carbanions for carbon-carbon bond formation.
• Pharmaceutical Intermediate Production: Used in the synthesis of active pharmaceutical ingredients (APIs) and complex chiral molecules.
• Fine Chemical Manufacturing: Key reagent for producing agrochemicals, flavors, fragrances, and liquid crystal precursors.
• Research & Development: Indispensable tool in academic and industrial laboratories for developing new synthetic methodologies and materials.
• Lithiation Agent: For the directed ortho-metalation of aromatic compounds in multi-step synthetic sequences.

Basic Information

Product Name	sec-Butyllithium
CAS No.	598-30-1
Molecular Formula	C4H9Li
Molecular Weight	64.06 g/mol
Synonyms	sec-BuLi; Lithium sec-butyl; Butyllithium, sec-; 1-Methylpropyllithium; (RS)-sec-Butyllithium; 2-Butyllithium; (±)-sec-Butyllithium; Lithium (1-methylpropyl)
EINECS	209-934-0

Quality Control

Our sec-Butyllithium is manufactured under stringent conditions to ensure batch-to-batch consistency and high reactivity. Quality is verified through comprehensive analytical testing, including titration for active content and GC analysis for hydrocarbon solvent purity. A Certificate of Analysis (COA) detailing assay, concentration (typically in cyclohexane or hexane), and impurity profile is provided with each shipment to ensure compliance with your specific application requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at temperatures between 2°C and 8°C. This product is highly volatile, easily oxidized, and reacts violently with water and air. Keep away from heat, sparks, and open flame. Use only in a certified fume hood with appropriate personal protective equipment.

Specification

Item	Specification
Appearance	Clear, colorless to slightly yellow solution
Assay (by Titration)	Contact for details
Concentration	Typically 1.0M to 1.4M in cyclohexane/hexane
Identification (IR)	Conforms
Solvent Content (GC)	>99%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.