Description

Lithium B-Isopinocampheyl-9-Borabicyclo[3.3.1]Nonyl Hydride is a highly specialized, chiral organoborane reagent used for stereoselective synthesis. This compound matters for its role as a powerful, enantiomerically enriched reducing agent and hydroborating agent in complex organic transformations. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the asymmetric synthesis of chiral intermediates.

Application

• Asymmetric Reduction of Prochiral Ketones: Enantioselective synthesis of secondary alcohols for pharmaceutical active ingredients.
• Chiral Hydroboration of Alkenes: Production of enantiomerically pure alkylboranes for subsequent cross-coupling reactions.
• Stereocontrolled Synthesis: Key reagent in the construction of complex natural products and fine chemicals with defined stereochemistry.
• Pharmaceutical Intermediate Manufacturing: Critical for creating chiral building blocks in drug discovery and development pipelines.
• Agrochemical Research: Used in the synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Methodology Development in Academic Labs: A valuable tool for developing new catalytic cycles and synthetic methodologies.

Basic Information

Product Name	Lithium B-Isopinocampheyl-9-Borabicyclo[3.3.1]Nonyl Hydride
CAS No.	100013-07-8
Molecular Formula	C₁₉H₃₂BLi
Molecular Weight	278.22 g/mol
Synonyms	Lithium (Isopinocampheyl)(9-BBN)hydride; Lithium B-Isopinocampheyl-9-BBN-Hydride; Lithium (1R,2S,5R)-(-)-Isopinocampheyl-9-borabicyclo[3.3.1]nonyl Hydride; (-)-B-Ipc-9-BBN-H Li salt; Lithium (Ipc)(9-BBN)hydride; Chiral 9-BBN Reducing Agent; Lithium trialkylborohydride reagent
EINECS	Contact for details

Quality Control

Every batch of our Lithium B-Isopinocampheyl-9-Borabicyclo[3.3.1]Nonyl Hydride is produced and handled under strict inert atmosphere conditions to ensure integrity. We employ advanced analytical techniques, including NMR spectroscopy and chiral HPLC, to verify chemical purity, enantiomeric excess (ee), and solution concentration. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. This material is hygroscopic (moisture-sensitive) and reacts with strong bases. For long-term stability, store under an inert atmosphere (argon or nitrogen) at 2-8°C. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder or suspension
Identification (NMR)	Conforms to structure
Assay (Titration)	≥ 95%
Enantiomeric Excess (HPLC)	≥ 99% ee
Solution Concentration (Typical)	1.0 M in THF or as specified

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.