Description

Trimethylphosphine is a highly reactive organophosphorus compound with the CAS number 594-09-2, serving as a versatile and fundamental ligand in organometallic chemistry and catalysis. Its strong electron-donating properties and small steric profile make it invaluable for constructing complex molecular frameworks and facilitating challenging chemical transformations. This essential reagent is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of catalysts, ligands, and specialty chemicals.

Application

• Catalyst and Ligand Synthesis: A key precursor for the preparation of transition metal catalysts used in cross-coupling reactions, hydrogenation, and hydroformylation.
• Pharmaceutical Intermediates: Employed in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs) requiring phosphorus-containing motifs.
• Agrochemical Production: Used in the manufacture of certain phosphorus-based pesticides, herbicides, and plant growth regulators.
• Material Science Research: Acts as a precursor for depositing phosphorus-containing thin films or for modifying surface properties in advanced materials.
• Organic Synthesis: Utilized as a nucleophilic phosphine reagent in various organic transformations, including the Wittig reaction and Mitsunobu reactions.
• Coordination Chemistry: Serves as a fundamental ligand to stabilize low-oxidation-state metals and create novel coordination complexes for study.

Basic Information

Product Name	Trimethylphosphine
CAS No.	594-09-2
Molecular Formula	C3H9P
Molecular Weight	76.08 g/mol
Synonyms	Phosphine, trimethyl-; Trimethylphosphane; TMP; Methylphosphine, trimethyl-; PMe3; NSC 66427
EINECS	209-823-2

Quality Control

Our Trimethylphosphine is produced and handled under stringent quality protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the rigorous demands of research and industrial-scale synthesis, ensuring reliable performance in your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and easily oxidized nature, this product must be stored under an inert atmosphere (argon or nitrogen) in a cool, well-ventilated area, away from heat and ignition sources. Recommended long-term storage temperature is 2-8°C. Containers must be kept tightly sealed to prevent moisture ingress and pressure build-up.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.