Description

3-(3-Trifluoromethylphenyl)Propionic Acid is a versatile fluorinated aromatic building block essential for advanced organic synthesis. Its value lies in the unique combination of the propionic acid moiety and the electron-withdrawing trifluoromethyl group, which imparts desirable metabolic stability and lipophilicity to target molecules. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of non-steroidal anti-inflammatory drugs (NSAIDs) and other bioactive molecules.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides, where the trifluoromethyl group enhances biological activity.
• Liquid Crystal Materials: Serves as a precursor for fluorinated liquid crystal compounds used in display technologies.
• Polymer Modification: Employed to introduce fluorinated aromatic units into polymer chains, altering thermal and chemical resistance properties.
• Organic Synthesis Building Block: Utilized in coupling reactions (e.g., amidation, esterification) to create complex fluorinated structures for material science.

Basic Information

Product Name	3-(3-Trifluoromethylphenyl)Propionic Acid
CAS No.	585-50-2
Molecular Formula	C10H9F3O2
Molecular Weight	218.17 g/mol
Synonyms	3-[3-(Trifluoromethyl)phenyl]propanoic Acid; 3-(3-Trifluoromethylphenyl)propanoic Acid; 3-(α,α,α-Trifluoro-m-tolyl)propionic Acid; m-Trifluoromethylhydrocinnamic Acid; 3-(3-(Trifluoromethyl)phenyl)propionic Acid; β-(3-Trifluoromethylphenyl)propionic Acid; NSC 3349
EINECS	209-548-5

Quality Control

Our 3-(3-Trifluoromethylphenyl)Propionic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	78 - 82 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.