Description

3-(Trifluoromethyl)Cyclohexanone is a versatile fluorinated ketone building block, valued for its unique combination of a cyclohexanone scaffold and a highly electronegative trifluoromethyl group. This structure imparts significant lipophilicity and metabolic stability, making it a critical intermediate in advanced synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the CF₃ group enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display and lighting technologies.
• Organic Synthesis Building Block: Employed in various organic transformations, including Grignard reactions, reductions, and nucleophilic additions, to introduce the trifluoromethylated cyclohexyl moiety.
• Flavor & Fragrance Chemistry: Used in the synthesis of complex, high-value aroma chemicals.
• Polymer Modification: Acts as a monomer or modifier to introduce fluorine into polymer chains, altering surface properties and chemical resistance.

Basic Information

Product Name	3-(Trifluoromethyl)Cyclohexanone
CAS No.	585-36-4
Molecular Formula	C7H9F3O
Molecular Weight	166.14 g/mol
Synonyms	3-(Trifluoromethyl)cyclohexanone; α,α,α-Trifluoro-m-toluic ketone; 3-Trifluoromethylcyclohexanone; Cyclohexanone, 3-(trifluoromethyl)-; 1-Trifluoromethyl-3-cyclohexanone; m-Trifluoromethylcyclohexanone
EINECS	209-540-5

Quality Control

Our 3-(Trifluoromethyl)Cyclohexanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and fluorides. The container should be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20/D)	1.420 - 1.430
Density (g/mL at 20°C)	1.20 - 1.30

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.