Description

4,4'-Difluorobenzil is a high-purity organic compound featuring a benzil core symmetrically substituted with fluorine atoms at the para positions. This fluorinated aromatic diketone serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in specialty chemical synthesis. It is essential for manufacturers in the pharmaceutical, agrochemical, and materials science sectors who require precise fluorination to modulate the biological activity and physical properties of their target molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and pesticides where fluorine incorporation enhances efficacy and environmental stability.
• Liquid Crystal & OLED Materials: Used in the production of fluorinated components for liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs) to improve thermal stability and electronic properties.
• Polymer Chemistry: Monomer or cross-linking agent for engineering high-performance polymers with enhanced chemical resistance and thermal characteristics.
• Organic Synthesis & Research: Versatile reagent for constructing complex fluorinated aromatic structures in academic and industrial R&D laboratories.
• Dye & Pigment Manufacturing: Intermediate for synthesizing specialized fluorinated dyes and pigments with unique color fastness and spectral properties.

Basic Information

Product Name	4,4'-Difluorobenzil
CAS No.	579-39-5
Molecular Formula	C14H8F2O2
Molecular Weight	246.21 g/mol
Synonyms	(4-Fluorophenyl)(4-fluorophenyl)ethanedione; 1,2-Bis(4-fluorophenyl)ethane-1,2-dione; Bis(4-fluorophenyl)glyoxal; 4,4'-Difluorobenzil; 4-Fluorobenzil; p,p'-Difluorobenzil; 1,2-Di(4-fluorophenyl)ethane-1,2-dione
EINECS	209-439-1

Quality Control

Our 4,4'-Difluorobenzil is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our production adheres to cGMP and ISO 9001 principles, ensuring reliability for critical applications in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider maintaining under an inert atmosphere (e.g., nitrogen or argon) to preserve stability and purity. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	142 - 146 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.