Description

1-Methoxy-2,4-Bis(Trifluoromethyl)Benzene is a high-value fluorinated aromatic building block, prized for its unique electronic and steric properties imparted by the trifluoromethyl groups. This compound is critical for advanced synthesis, enabling the development of materials and molecules with enhanced stability, lipophilicity, and performance characteristics. It is primarily sought after by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty materials industries for applications in catalysis, ligand design, and the synthesis of complex organic frameworks.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs for metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the trifluoromethyl groups contribute to biological activity and environmental persistence.
• Ligand & Catalyst Development: Acts as a precursor for sophisticated ligands in transition metal catalysis, enabling highly selective and efficient chemical transformations.
• Specialty Materials: Incorporated into the synthesis of advanced polymers, liquid crystals, and electronic materials to modify solubility, thermal stability, and optical properties.
• Organic Synthesis Building Block: Provides a versatile, electron-deficient aromatic core for nucleophilic aromatic substitution and cross-coupling reactions in complex molecule assembly.

Basic Information

Product Name	1-Methoxy-2,4-Bis(Trifluoromethyl)Benzene
CAS No.	577-05-9
Molecular Formula	C10H6F6O
Molecular Weight	256.15 g/mol
Synonyms	2,4-Bis(trifluoromethyl)anisole; 1-Methoxy-2,4-bis(trifluoromethyl)benzene; 2,4-Bis(trifluoromethyl)methoxybenzene; Anisole, 2,4-bis(trifluoromethyl)-; Benzene, 1-methoxy-2,4-bis(trifluoromethyl)-; α,α,α,α',α',α'-Hexafluoro-2,4-dimethylanisole
EINECS	Contact for details

Quality Control

Our production of 1-Methoxy-2,4-Bis(Trifluoromethyl)Benzene adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.