Description

2-(Trifluoroacetyl)Indan-1-One is a versatile fluorinated organic building block characterized by its indanone core and reactive trifluoroacetyl group. This compound matters for its role as a key intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where the introduction of fluorine atoms is crucial for modulating biological activity and metabolic stability. Industries that need it include pharmaceutical R&D for drug discovery, agrochemical manufacturers developing novel active ingredients, and advanced material scientists working on specialty polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the trifluoromethyl group enhances lipophilicity and environmental stability.
• Material Science Research: Serves as a precursor for fluorinated organic semiconductors, liquid crystals, and other advanced electronic materials.
• Organic Synthesis & Catalysis: Employed in academic and industrial research for constructing complex heterocycles and as a substrate in fluorination and cross-coupling reactions.
• Dye & Pigment Industry: Acts as an intermediate for synthesizing specialized fluorinated dyes and pigments with unique optical properties.

Basic Information

Product Name	2-(Trifluoroacetyl)Indan-1-One
CAS No.	576-12-5
Molecular Formula	C11H7F3O2
Molecular Weight	228.17 g/mol
Synonyms	1-Indanone, 2-(trifluoroacetyl)-; 2-Trifluoroacetyl-1-indanone; 2-(Trifluoroacetyl)-1-indanone; α-(Trifluoroacetyl)indan-1-one; 1-Oxo-2-(trifluoroacetyl)indane; 576-12-5; 2-Trifluoroacetylindan-1-one; 2-(Trifluoroacetyl)-1H-inden-1-one
EINECS	Contact for details

Quality Control

Our 2-(Trifluoroacetyl)Indan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure compliance with stringent industry standards. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our commitment to cGMP principles and REACH compliance ensures a reliable and traceable supply for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.